Sneha acted in two films in 2003, Vaseegara with Vijay and a heroine-oriented double role in Parthiban Kanavu.
While the former was a failure, the latter was a huge success.
The years 20 saw her acting in Telugu films such as Sankranthi with Venkatesh, Radha Gopalam with Srikanth, Sri Ramadasu with Nagarjuna, and Thuruppu Gulan with Mammootty winning plaudits at box office, while others released in the respective years turning as average grosser at the box office.
She played the role of a commercial sex worker in Selvaraghavan's Pudhupettai, starring Dhanush. In the year 2006, she made her debut into Kannada film industry through Ravi Shastri, which tanked at the box office.
Co-starring Cheran, the film opened to critical acclaim and emerged a sleeper hit, while fetching Sneha plaudits and several accolades.
A review from Sify noted that she was "superb as Sala a woman torn by the dualities of her existence", labelling it as her "career best performance".
She was signed by Susi Ganeshan for his directorial debut Virumbugiren in 2000, which however became long delayed and Ennavale opposite Madhavan became her first Tamil release. Nee Romba Azhaga Irukke, Unnai Ninaithu and April Madhathil.